What are the most common side effects of estradiol?

Estradiol side effects can include heartburn.

Estradiol is a medication that contains a form of the hormone estrogen. This is a very powerful hormone and using topical or oral forms can cause serious side effects, including an increased risk of heart attack, blood clots, endometrial cancer, and breast cancer. Other side effects of estradiol include headaches, nausea, heartburn, and mood swings. Children should never be exposed to estradiol unless prescribed by a medical professional, and care should be taken when topical forms are used to avoid accidentally spilling the drug on others.

Women who use estradiol may notice breast enlargement and tenderness.

People can use topical or oral forms of estradiol to treat some symptoms associated with estrogen loss due to menopause or as hormone replacement when the ovaries stop working or are removed. It can also help protect women against osteoporosis. A less common use is during end-stage prostate cancer in men or to alleviate some symptoms of breast cancer. It is available in various strengths as a tablet, transdermal patch, cream and topical spray.

Nausea and stomach pain are common side effects of estradiol.

Most guidelines for using this medication suggest that it be used for the shortest possible periods of time to reduce the chances of developing many of the more serious side effects of estradiol. Using this hormone increases the risk of heart attack, stroke, deep vein thrombosis, and blood clots in some women, especially if they smoke or have a history of any of these conditions. When used as hormone replacement, estradiol is sometimes combined with progesterone; studies have shown that this combination can increase a woman’s risk of breast cancer.

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Estradiol side effects can include hair loss.

Headache is one of the most common side effects of estradiol and can affect up to 20% of people who take it. Other side effects include dizziness, confusion, and trouble speaking. Mood swings, including depression and anxiety, can also occur. As this hormone can affect the cardiovascular system, any chest pain, numbness or weakness on one side of the body, or difficulty breathing, could be a sign of a heart attack or heart attack. These symptoms should be reported to a healthcare professional immediately.

Headaches are a common side effect of estradiol.

This hormone, which works by stimulating the growth of female reproductive organs, can cause breast tenderness or pain, as well as increase breast growth in some people. It is often used to relieve vaginal dryness and inflammation, but it can also cause itchiness and discharge. Some women experience spotting between menstrual periods and other unusual vaginal bleeding and changes in their menstrual cycles. It also increases the risk of yeast infections.

Breast tenderness is a common side effect of estradiol.

People who use topical estradiol may experience redness or irritation where the drug is applied. Flu-like symptoms, arthritic pain, and hair loss are relatively common. Many people also report problems with their digestive systems, including stomach pain, nausea, vomiting, and bloating.

Certain populations should observe some other side effects of estradiol. People who have diabetes and taking this medication should carefully monitor their blood sugar levels as they can change. Those who have a thyroid disorder should also watch their thyroid levels carefully. Even in people without hypothyroidism, prolonged use of estradiol can reduce thyroid hormone levels to below normal levels.

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Estradiol should be used for the shortest period of time possible.

Men and children should not be exposed to estradiol in most cases as it can cause breast development. Girls who touch this medication may start puberty prematurely. Pregnant women should not take estradiol because it can increase a child’s risk of developing abnormalities in the urinary and genital systems, as well as certain cancers later in life. It is unclear whether this medication is passed to an infant through breast milk, so women who are breastfeeding should speak with a medical professional before using it.

There is also some concern about estradiol’s potential to cause dementia, as has been seen in some older patients who use it. In general, women who are past menopause are discouraged from using this medication, especially for the long term.

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